- Original Article
- Infection
- Usefulness of interferon-γ release assay for the diagnosis of latent tuberculosis infection in young children
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Ki Wook Yun, Young Kwang Kim, Hae Ryun Kim, Mi Kyung Lee, In Seok Lim
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Clin Exp Pediatr. 2016;59(6):256-261. Published online June 30, 2016
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Purpose Latent tuberculosis infection (LTBI) in young children may progress to severe active tuberculosis (TB) disease and serve as a reservoir for future transmission of TB disease. There are limited data on interferon-γ release assay (IGRA) performance in young children, which our research aims to address by investigating the usefulness of IGRA for the diagnosis of LTBI. MethodsWe performed a tuberculin skin... |
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- Epidemiologic and clinical features in children with acute lower respiratory
tract infection caused by human metapneumovirus in 2006-2007
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Gwi Ok Park, Ji Hyun Kim, Jae Hee Lee, Jung Ju Lee, Sin Weon Yun, In Seok Lim, Dong Keun Lee, Eung Sang Choi, Byoung Hoon Yoo,, Mi Kyung Lee, Soo Ahn Chae
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Clin Exp Pediatr. 2009;52(3):330-338. Published online March 15, 2009
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Purpose : The causes of acute lower respiratory tract infection (ALRTI) are mostly attributable to viral infection, including respiratory syncytial virus (RSV), parainfluenza virus (PIV), influenza virus A/B (IFV A/B), or adenovirus (ADV). Several Korean studies reported human metapneumovirus (hMPV) as a common pathogen of ALRTI. However, studies on seasonal distribution and clinical differences relative to other viruses are insufficient,... |
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- Case Report
- Partial trisomy of chromosome 18q11.2-q12: A case report
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Ah Ra Cho, Hye Ryoun Kim, Mi Kyung Lee, Sin Weon Yun, Jung Ju Lee
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Clin Exp Pediatr. 2009;52(10):1171-1174. Published online October 15, 2009
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Edwards syndrome, also called trisomy 18, is one of the most common autosomal anomalies. The survival rate of patients with Edwards syndrome is very low and its characteristic findings include cardiac malformations, mental retardation, growth retardation, specific craniofacial anomalies, clenched hands, rocker-bottom feet, and omphalocele. Compared with the classic Edwards syndrome, the symptom of partial duplication of chromosome 18 is... |
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- Original Article
- Clinical significance of serum vascular endothelial growth factor in Kawasaki disease
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Ho Seok Lee, Sin Weon Yun, Young Soo Jung, Soo Ahn Chae, In Seok Lim, Dong Keun Lee, Eung Sang Choi, Byung Hoon Yoo, Mi Kyung Lee
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Clin Exp Pediatr. 2007;50(10):995-1004. Published online October 15, 2007
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Purpose : Kawasaki disease is a systemic vasculitis, leading cause of pediatric acquired heart disease. Vascular endothelial growth factor (VEGF) has functions as vascular permeability factor, plays an important role in coronary artery lesion (CAL). We studied the clinical significance of serum VEGF in Kawasaki disease.
Methods : Kawasaki group was 49 patients, and control group was 15 patients. Diagnosis followed... |
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- Interaction of the mec Regulator Genes in Methicillin Resistant Staphylococcus
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Young Choi, In Seok Lim, Tae Sub Shim, Mi Kyung Lee, Ae Ja Park
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Clin Exp Pediatr. 1998;41(9):1224-1233. Published online September 15, 1998
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Purpose : Low-affinity penicillin-binding protein PBP 2a encoded by mecA is closely related to methicillin resistance in staphylococci, and the expression of PBP 2a is controlled by regulator elements encoded by mecR1 and mecI. Deletion or mutation which occurred in mecI is considered to be associated with constitutive production of PBP 2a. We investigated the distribution of mec regulator genes... |
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